Advanced Blood Gas
Advanced ABG interpretation including Anion Gap and Delta Gap analysis.
Blood Gas Parameters
Enter values from the laboratory report.
Clinical Context & Significance
Acid-base balance during cardiopulmonary bypass is essential for cellular enzymatic function and metabolic stability. The Advanced ABG tool provides a systematic approach to identifying complex acid-base disturbances beyond simple pH and $pCO_2$ analysis.
The Anion Gap (AG)
The Anion Gap represents the concentration of unmeasured anions in the plasma (AG = Na+ - [Cl- + HCO3-]). A normal AG is typically 8-12 mEq/L. An elevation (HAGMA) during CPB is most frequently caused by lactic acidosis, often indicative of an oxygen supply/demand mismatch or poor tissue perfusion.
Delta Gap Analysis
The Delta Gap helps identify "hidden" mixed acid-base disorders. By comparing the rise in the anion gap to the fall in bicarbonate, clinicians can determine if there is a secondary metabolic alkalosis (common after massive transfusion or diuretic use) or a concurrent normal-gap acidosis.
Clinical Reference: Rose BD, Post TW. Clinical Physiology of Acid-Base and Electrolyte Disorders. 5th ed. McGraw-Hill Professional.