Formula References

The core formulas used across the Perfusion Pro calculators.

Academic Formula References and Clinical Perfusion Literature

Physiological Principles & Clinical Context

All clinical calculators in the Perfi suite are built on internationally accepted physical, physiological, and mathematical formulas validated by peer-reviewed literature and perfusion societies. Perfusion calculations are an essential part of clinical decision support, but they must always be verified manually and interpreted alongside the patient's comprehensive clinical status and real-time hemodynamic monitoring.

Clinical Targets & Safe Ranges

  • Validation protocols: Formulas are peer-reviewed and mapped to standard textbook models.
  • Goal-directed standards: Aligns with SACP, AACP, and AmSECT guidelines.
  • Continuous verification: Manual calculations should be performed as redundant checks for high-stakes decisions.

Mathematical Formulation

  • ƒFull compilation of hemodilution, anticoagulation, gas correction, and oxygenation formulas is represented across our calculators.

Academic & Clinical References

  1. Gravlee GP, et al. Cardiopulmonary Bypass: Principles and Practice. 4th ed. 2015.
  2. Ranucci M, et al. Goal-directed perfusion and acute kidney injury. J Thorac Cardiovasc Surg. 2018.
  3. Standard guidelines of AmSECT, EBCP, and STS.